When you’re first fitted for new dentures, it’s normal to experience minor irritations, which should fade as your mouth becomes accustomed to the denture or partial. The period of discomfort can vary from patient to patient based on your treatment. If you’ve previously worn dentures and now have a new set, you know what to expect, but they still may take some getting used to as well as possibly needing adjusted to fit comfortably. Similarly, if you had some natural teeth present that were removed at the time of the new dentures, the areas where the extractions were performed may be painful or uncomfortable for up to several weeks after the removal of the teeth. Regular visits to your dentist to adjust the dentures as you go through the normal healing process are recommended.